pseudotyped

These studies establish the potential of cocal-pseudotyped lentiviral vectors for a variety of scientific and therapeutic gene transfer applications, including Junior (Assistant-Associate) Professor in Cell Biology and Anatomy

Naturejobs - All Jobs Grant D Trobridge 2010

VSVG-pseudotyped lentivirus to deliver human factor IX to non-chimeric SCID mice

PLoS ONE Alerts: New Articles Ryan M. O'Connell et al. 2010

Cocal-pseudotyped lentiviral vectors can be produced at titers as high as with VSV-G, have a broad tropism, and are stable, allowing for efficient concentration by centrifugation.

Naturejobs - All Jobs Grant D Trobridge 2010

They are almost always pseudotyped with the envelope glycoprotein of vesicular stomatitis virus (VSV-G) due to the high titers that can be achieved, their stability, and broad tropism.

Naturejobs - All Jobs Grant D Trobridge 2010

VSV-G pseudotyped retroviruses were prepared according to standard techniques.

PLoS Biology: New Articles Marcel A. T. M. van Vugt et al. 2010

We generated a novel cocal vesiculovirus envelope glycoprotein plasmid and compared the properties of lentiviral vectors pseudotyped with cocal, VSV-G, and a modified feline endogenous retrovirus envelope glycoprotein (RD114/TR).

Naturejobs - All Jobs Grant D Trobridge 2010

Kimpton J, Emerman M (1992) Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene.

PLoS ONE Alerts: New Articles 2009

The lentiviral system, pseudotyped with the VSV-G envelope protein, is an attractive system for viral packaging and delivery of shRNA constructs due to its broad tropism and nonreceptor-mediated delivery, its ability to integrate into the genome for stable gene silencing, and the fact that it does not require a mitotic event for integration into the genome.

GEN News Highlights 2009

When appropriately pseudotyped, these viral particles can transduce a broader spectrum of cell lines and overcome issues faced in standard transfection methods.

GEN News Highlights 2009

Instead of focusing exclusively on how the virus enters the cell, like other pseudotyped screening assays, explains Dr. Porotto, the researchers were able to consider how Hendra matures, buds, and exits the cell, and to screen for compounds that interfere with its development at various stages.

EurekAlert! - Breaking News 2009