Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun An antibiotic, C22H29N7O5, obtained from the soil bacterium Streptomyces alboniger, that is used experimentally as an inhibitor of protein synthesis.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An
antibiotic that is a strong inhibitor ofprotein translation , having the chemical formula C22H29N7O5.
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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Other common antibiotics, including hydromycin-B and puromycin, have also been developed for stable cell selection, as have genetic markers.
Archive 2005-10-01 2005
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One day after infection, 0.25 µg/ml puromycin was added to select infected cells.
PLoS ONE Alerts: New Articles Munehiro Uemura et al. 2010
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Cultures were initiated with various dilutions of BCN2081 L1 larvae (carrying a single-copy integrated puromycin resistance transgene) with wild-type N2 larvae.
Naturejobs - All Jobs Jennifer I Semple 2010
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Infected cells were selected with 2 µg/ml puromycin. pRS-53BP1-infected MCF7 cells were subsequently treated with 4 µM nutlin-3 to select for cells with a functional 53BP1 knockdown
PLoS Biology: New Articles Marcel A. T. M. van Vugt et al. 2010
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(Exchr.) array with the puromycin resistance gene and mab-5 under a heat shock-inducible promoter, with or without puromycin selection.
Naturejobs - All Jobs Jennifer I Semple 2010
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Previously, we demonstrated that cytochrome P450 2B1 (CYP2B1) can generate reactive oxygen species in puromycin aminonucleoside (PAN) - induced nephrotic syndrome, an animal model of minimal-change disease in humans.
Naturejobs - All Jobs Niu Tian 2010
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Stable clones or mixed populations were cultured in the presence of puromycin (1 µg/ml).
PLoS ONE Alerts: New Articles Daniela Trisciuoglio et al. 2010
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Retrovirus-infected cells were maintained in the presence of puromycin more than two weeks before lysate preparation. doi: 10.1371/journal. pone.0009846.g007
PLoS ONE Alerts: New Articles Munehiro Uemura et al. 2010
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Chr. 17, chromosome 17; hyg, hygromycin resistance gene; neoSD, neo splice donor; SA neo, splice acceptor neo; puro, puromycin resistance gene.
Naturejobs - All Jobs Deniz Simsek 2010
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Many ocular cells including RGC5 are very resistant to various commonly used selection antibiotics, including G418, zeocin, and puromycin.
PLoS ONE Alerts: New Articles Hongyu Ying et al. 2010
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