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Examples
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The data also showed that Bexsero, when administered alone, had a reactogenicity profile that was comparable to those of the routine vaccines1.
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Local reactogenicity assessments included pain, tenderness, induration, and erythema.
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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Descriptive summaries with frequencies of reactogenicity measures, immune assay response rates and geometric mean titer results are presented along with nonparametric comparisons of antibody levels and reaction severity.
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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The distinct differences in local reactogenicity between the current study and the studies evaluating therapeutic vaccines in
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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Therefore, in human subjects who have underlying conditions that may affect immune competence, reactogenicity does not appear to be a limiting factor.
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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Although vaccines formulated with mineral oil have been administered to more than 1 million people since 1945, with the emergence of aluminum-based adjuvants, they fell out of favor because of the reactogenicity profile and potential for causing sterile abscesses
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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Although the product was shown to be immunogenic after two doses in this study, immunogenicity was not fully evaluated because the trial was stopped early due to unacceptable local reactogenicity.
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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Montanide ISA-51 has also been frequently used as an adjuvant in a variety of therapeutic cancer vaccines in which reactogenicity is never described as greater than moderate or Grade
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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This trial was prematurely terminated due to unexpected systemic reactogenicity.
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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It is also possible that antigenic differences could explain the differences in systemic reactogenicity between this study and the one evaluating malaria antigens with IFA.
PLoS ONE Alerts: New Articles Barney S. Graham et al. 2010
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