recombinational love

recombinational

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective genetics Of or pertaining to genetic recombination

Etymologies

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Examples

  • Renilla and firefly luciferase genes to create pcDNA3. 1-hODC-IRES. pcDNA3. 1-V5-ZNF9 was constructed by insertion of the PCR-generated full-length open reading frame of human ZNF9 into pENTR and subsequent recombination into pcDNA3. 1/nV5-Dest (Invitrogen) by recombinational cloning (Invitrogen).

    PLoS ONE Alerts: New Articles Morgan A. Sammons et al. 2010

  • Germline mutations in a number of genes involved in the recombinational repair of DNA double-strand breaks are associated with predisposition to breast and ovarian cancer.

    Naturejobs - All Jobs Alfons Meindl 2010

  • However the divergence between the strains was such that it was difficult to consistently distinguish mutational and recombinational SNPs, as the frequency of mutations was higher so that putative recombinant segments were not easily distinguished.

    PLoS ONE Alerts: New Articles Zhemin Zhou et al. 2010

  • In addition, sequences at the genomic termini were believed to be recombinational hot-spots due to the induction of an additional double-strand break mechanism or due to the high GC content at the DNA ends

    PLoS ONE Alerts: New Articles Felix Wussow et al. 2009

  • Fasullo MT, Davis RW (1988) Direction of chromosome rearrangements in Saccharomyces cerevisiae by use of his3 recombinational substrates.

    PLoS ONE Alerts: New Articles 2008

  • Wolner B, van Komen S, Sung P, Peterson CL (2003) Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast.

    PLoS ONE Alerts: New Articles 2008

  • Decreased translocation formation by recombinational repair of double-strand breaks in telomerase-deficient yeast suggests that the reemergence of telomerase expression observed in many human tumors may further stimulate genome rearrangement.

    PLoS ONE Alerts: New Articles 2008

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