renal failure

from The American Heritage® Dictionary of the English Language, 5th Edition.

• noun Acute or chronic malfunction of the kidneys resulting from any of a number of causes, including infection, trauma, toxins, hemodynamic abnormalities, and autoimmune disease, and often resulting in systemic symptoms, especially edema, hypertension, metabolic acidosis, and uremia.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

• noun inability of the kidneys to excrete wastes and to help maintain the electrolyte balance