from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Any of various enzymes that break down RNA. Also called RNase.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Any of a group of enzymes which catalyzes the hydrolysis of ribonucleic acid.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a transferase that catalyzes the hydrolysis of ribonucleic acid
Sorry, no etymologies found.
I joined a project on the protein ribonuclease, but shortly afterwards met Rosalind Franklin, who had moved to Birkbeck earlier and had begun working on tobacco mosaic virus.
We not only wanted to know what the amino acid sequence of an enzyme such as ribonuclease was, but we tried to find out as much as we could about what made it an enzyme and after we had taken that particular enzyme about as far as we thought we could profitably go, we turned to a number of others which have been listed in the Nobel Lecture.
This enzyme, ribonuclease P (RNase P), was readily identifiable.
Anfinsen had shown, with the enzyme ribonuclease, that the information for a protein assuming a specific three-dimensional structure is inherent in its amino-acid sequence, and this discovery was the starting point for studies of the mechanism of protein folding, one of the major areas of present-day biochemical research.
Moore and Stein had determined the amino-acid sequence of ribonuclease, but they received the prize for discovering anomalous properties of functional groups in the enzyme's active site, which is a result of the protein fold.
Cohn and her lab had access to some of the finest machinery and expertise in magnetic resonance, and over the next two decades she used these tools to look at numerous enzyme-substrate complexes like creatine kinase, pyruvate kinase, and ribonuclease, just to name a few.
Behe versus ribonuclease; the origin and evolution of protein-protein binding sites
Continue reading “Behe versus ribonuclease; the origin and evolution of protein-protein binding sites”.
For example, by random folding, the amino-acid chain of the enzyme ribonuclease, a small protein, could adopt more than 1040 different shapes, which would take billions of years to explore.
It was also demonstrated that a ribonuclease III-like nuclease, called Dicer, is responsible for the processing of dsRNA to short RNA34.