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Examples
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Chinese soapberry tree, which contains the natural cleaning agent saporin.
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The conjugation of the mAbTCR23 antibody to saporin, a highly effective intracellular cytotoxic agent, did not affect the biological activity of the antibody.
THE MEDICAL NEWS Editors 2010
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Robertson RT, Gallardo KA, Claytor KJ, Ha DH, Ku KH, et al. (1998) Neonatal treatment with 192 IgG-saporin produces long-term forebrain cholinergic deficits and reduces dendritic branching and spine density of neocortical pyramidal neurons.
PLoS ONE Alerts: New Articles Nyresa C. Alves et al. 2010
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The conjugation of the mAbTCR23 antibody to saporin, a highly effective intercellular cytotoxic agent, did not affect the biological activity of the antibody.
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To test this idea, we developed a specific immunotoxin consisting of an anti-melanopsin antibody conjugated to the ribosome-inactivating protein, saporin.
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