from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of a family of transmembrane proteins involved in the protein complex responsible for connecting the muscle fibre cytoskeleton to the extracellular matrix, preventing damage to the muscle fibre sarcolemma through shearing forces.


Sorry, no etymologies found.


  • These mutations created a stop codon that led to a - sarcoglycan deficiency, and we therefore diagnosed these two patients as having LGMD2C.

    BioMed Central - Latest articles

  • The remaining two patients had normal dystrophin expression but absence of - sarcoglycan in skeletal muscle.

    BioMed Central - Latest articles

  • Sampaolesi M, Torrente Y, Innocenzi A, Tonlorenzi R, D'Antona G, et al. (2003) Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts.

    PLoS ONE Alerts: New Articles

  • Limb-girdle muscular dystrophy actually describes more than 19 disorders that occur because patients have a faulty alpha-sarcoglycan gene.

    University of Florida News


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