from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A usually fatal disease of sheep and goats, marked by chronic itching, loss of muscular coordination, and progressive degeneration of the central nervous system.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A degenerative prion disease of sheep and goats that attacks the central nervous system.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. a fatal disease of sheep characterized by chronic itching and loss of muscular control and progressive degeneration of the central nervous system


from The American Heritage® Dictionary of the English Language, 4th Edition

From scrape (from the scraping of itching parts of the skin against objects).

from Wiktionary, Creative Commons Attribution/Share-Alike License

From scrape +‎ -ie.


  • Although well-established in scrapie and, more recently, in BSE, comparatively little is known about the possibility of prion strains in chronic wasting disease (CWD), a disease affecting free ranging and captive cervids, primarily in North America.

    CWD Worse Than Ever In Wisconsin Counties

  • Extensive search through the model parameter space produced only long-term scrapie persistence for ε3 ≥ 0.01.

    PLoS ONE Alerts: New Articles

  • However, to test the broader implications of our results, simulations carried out with different dominance assumptions (i.e. SL/RH genotypes are also susceptible to scrapie and have different lamb mortality rates than SL/SL genotypes) resulted in similar long-term scrapie persistence patterns, albeit for different ranges of model parameters.

    PLoS ONE Alerts: New Articles

  • BSE originated in the early 1980s when cattle were fed by-products from sheep suffering from a brain disease called scrapie, whose cause appears to be a chemically stable protein aggregate called a prion.

    On Food and Cooking, The Science and Lore of the Kitchen

  • The steady state prevalence is however the same for different values of β1 corresponding to long-term scrapie persistence (

    PLoS ONE Alerts: New Articles

  • According to Richard Rhodes '"Deadly Feasts", all about the mutation of the disease called "scrapie" in sheep that became BSE in cows, then Creutzfeld-Jakob in humans, those unused brains and bones have been ground up and used in fertilizer as well as, at one time, cattle feed.

    Your Right Hand Thief

  • For many years after their discovery as the agents of some rare neurodegenerative diseases in mammals, such as scrapie in sheep and human Creutzfeldt-Jakob disease and kuru, prions have remained a truly esoteric research topic.

    Of Prions and People - The Panda's Thumb

  • "I didn't drive it particularly well, so I was a little 'scrapie' on the front nine," he said.

    Columnist: Keith Groller

  • Other prion diseases, in animals, there is a disease of cattle called BSE or bovine spongiform encephalopathy (commonly called mad cow disease), in sheep there is "scrapie" and in humans, there is GerstmannSträusslerScheinker syndrome (GSS), fatal familial insomnia (FFI) and kuru-kuru in humans in Papua New Guinea. - Articles related to Japan suspends beef exports over foot-and-mouth

  • Prions, infectious proteins that carry diseases such as scrapie, chronic wasting disease and mad cow disease, have received the bulk of the attention since the wastewater plant began deciding whether to take the waste, but a variety of other substances could come through the high-heat, high-pressure chemical digester Cornell will use to liquefy 750,000 pounds per year of animal carcasses and infectious bedding. -


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