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Examples
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This last activity involves an RNA unit directly binding a small-molecule metabolite, which switches the RNA into a conformation that activates its intrinsic self-cleavage activity (6).
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FADD mediates the recruitment of caspase-8 to tumor necrosis factor receptor 1 (TNF-R1), where caspase-8 becomes activated, presumably by self-cleavage, and in turn initiates a proteolytic cascade that ultimately leads to apoptosis.
WN.com - Articles related to DTI favors zero tariffs on cement, wheat 2010
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FADD mediates the recruitment of caspase-8 to tumor necrosis factor receptor 1 (TNF-R1), where caspase-8 becomes activated, presumably by self-cleavage, and in turn initiates a proteolytic cascade that ultimately leads to apoptosis.
WN.com - Articles related to DTI favors zero tariffs on cement, wheat 2010
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They shared conserved flanking sequences, were apparently differentially transcribed in a variety of plant tissues, and were capable of self-cleavage, suggesting that they had genuine, but as yet unknown, biological functions in plants and were not merely remnants of viral genomic incorporation.
News from The Scientist Sean P. Ryder 2010
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Perhaps some of them anneal to targets to form RNA enzymes, leading to self-cleavage.
News from The Scientist Sean P. Ryder 2010
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The low pH also activates the enzyme precursor pepsinogen into the active enzyme pepsin by self-cleavage.
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The low pH also activates the enzyme precursor pepsinogen into the active enzyme pepsin by self-cleavage.
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