from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Immunologically reactive to itself. Used of a cell or antibody.


Sorry, no etymologies found.


  • So far, early studies in MS populations are promising, indicating that Rituxan does lead to rapid depletion of self-reactive B cells.

    The Autoimmune Epidemic

  • These self-reactive T cells stimulate other immune cells to produce autoantibodies that attach to the perfectly fine, healthy cells within our body—in any organ or tissue—and cause cells to die.

    The Autoimmune Epidemic

  • Some of these are self-reactive (like on Elventh Hour, but without the picking up metals from their substrate part) in that they spread over the glass surface and bond with it.

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  • When the immune system is regarded as essentially self-reactive and interconnected, the

    The Impulse of Breathing

  • The first T cells to be positively selected and activated in the thymus are self-reactive CD4 T cells that thus become “regulatory.”

    The Impulse of Breathing

  • In other words, immune regulation in this theory is based on the reactivity of antibodies (and later lymphocytes) with their own repertoire to form a set of self-reactive, self-reflective, self-defining immune activities.

    The Impulse of Breathing

  • Burnet's theory proposed that the animal, during prenatal development, exercised a purging function of self-reactive lymphocytes

    The Impulse of Breathing

  • However, little is known about their role in autoimmune diabetes, a disease characterized by the reduction of insulin production subsequent to destruction of pancreatic β-cells by a polyclonal population of self-reactive T-cells.

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  • Medullary thymic epithelial cells (mTECs), acting together with MHC class II + dendritic cells, function to negatively select thymocytes that bear high affinity self-reactive TCRs

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  • This knowledge should help us identify more specific therapeutic targets that will improve the treatment of diseases resulting from self-reactive or malignant B cells.

    Health News from Medical News Today


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