Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A drug being researched for the treatment of certain lung cancers and other disorders.

Etymologies

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Examples

  • Patient biomarker analysis from the APPRAISE Phase 2b randomized discontinuation study of seliciclib in patients with NSCLC.

  • Continued collection of patient specimens from the APPRAISE randomized, double-blinded, randomized discontinuation, Phase 2b study of seliciclib in patients with NSCLC who failed at least two prior therapies.

  • The new information was potentially exciting for seliciclib because lung cancer with KRAS mutations has proven to be resistant to treatment with currently approved drugs like Tarceva and Erbitux.

    Biotech Stock Mailbag: Cyclacel Pharma - TheStreet

  • However With seliciclib news supposedly out this month or any time before the end of year it makes me question the results in seliciclib.

    Biotech Stock Mailbag: Cyclacel Pharma - TheStreet

  • Fast forward to January, when a research paper was published showing that seliciclib was highly effective at killing non-small cell lung cancer cells with a mutated copy of a gene known as KRAS.

    Biotech Stock Mailbag: Cyclacel Pharma - TheStreet

  • In August 2008, an independent data safety monitoring committee concluded that seliciclib wasn't likely to demonstrate an improvement in progression-free survival because there was no efficacy trend in favor of seliciclib-treated patients compared to patients treated with best supportive care at that time.

    Biotech Stock Mailbag: Cyclacel Pharma - TheStreet

  • I think it's a good idea to keep expectations tempered for seliciclib, Cylcacel's experimental lung cancer drug.

    Biotech Stock Mailbag: Cyclacel Pharma - TheStreet

  • The study was allowed to continue, however, because seliciclib was safe and there wasn't enough data to reach a definitive conclusion about the study's outcome.

    Biotech Stock Mailbag: Cyclacel Pharma - TheStreet

  • The new research suggested a way by which seliciclib might serve an unmet medical need benefiting patients with KRAS-mutated lung cancer.

    Biotech Stock Mailbag: Cyclacel Pharma - TheStreet

  • CYCC said topline results from a mid-stage clinical study showed oral seliciclib as a third or more line treatment in patients with non-small cell lung cancer did no better than a placebo in terms of progression free survival.

    Pfizer, Adolor End Collaboration to Develop Pain Meds: Biotech's Latest Troubles - Seeking Alpha

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