serine-threonine love

Help Wordnik hunt for a million missing words by backing our Kickstarter!



Sorry, no definitions found.


Sorry, no etymologies found.


  • Mycobacterium tuberculosis dephosphorylates serine-threonine kinases PknA and PknB.

    PLoS ONE Alerts: New Articles

  • IL-33 reverses the TLR4-induced reduction of CXCR2 expression in neutrophils via the inhibition of expression of G protein-coupled receptor kinase-2 (GRK2), a serine-threonine protein kinase that induces internalization of chemokine receptors

    Naturejobs - All Jobs

  • Akt is a serine-threonine kinase and is one of the main targets positively regulated by PI3K.

    PLoS ONE Alerts: New Articles

  • Activation of the IGF1R leads to phosphorylation of insulin-receptor-substrates and activation of the cytosolic serine-threonine MAP kinases and Akt kinases that induce the translocation of transcription factors to the cell nucleus, thereby initiating specific gene expression programmes

    PLoS ONE Alerts: New Articles

  • WNK1 expression have low BP, consistent with a gene-dosage effect of WNK1, a serine-threonine kinase regulating numerous ion channels involved in sodium and potassium transport

    PLoS ONE Alerts: New Articles

  • Jurkat E6. 1 T cells have deficiencies in the expression of lipid phosphatases PTEN and SHIP, leading to the constitutive activation of AKT, a serine-threonine kinase important for cell survival, and other downstream signaling molecules

    PLoS ONE Alerts: New Articles

  • WNK kinases are serine-threonine kinases with an atypical placement of the catalytic lysine.

    Journal of Biological Chemistry current issue

  • Immunoprecipitation studies revealed that gp96 co-immunoprecipitates with the serine-threonine protein phosphatase 5 (PP5), identified as a negative modulator of the mitogen extracellular kinase (MEK) - ERK pathway, in unstressed wild-type and post-hypoxic Tlr2-deficient RTECs.

    Journal of Biological Chemistry current issue

  • However, staurosporine, a broad spectrum kinase inhibitor that blocks serine-threonine as well as tyrosine kinases

    PLoS ONE Alerts: New Articles

  • All described eukaryotic aromatic amino acid hydroxylases are phosphoproteins whose activity is regulated by a series of serine-threonine kinases.

    PLoS ONE Alerts: New Articles


Log in or sign up to get involved in the conversation. It's quick and easy.