from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Showing a negative reaction to a test on blood serum for a disease, especially syphilis or AIDS.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. : Testing negative for a given pathogen, especially HIV.
  • adj. : Having seronegative blood serum.


from Wiktionary, Creative Commons Attribution/Share-Alike License

From sero- +‎ negative.


  • Dr. Chang-Miller's primary field is rheumatology with special interests in inflammatory joint diseases called seronegative spondyloarthropathies such as ankylosing spondylitis and psoriatic arthritis.

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  • Crohn learned about Delta 32 after he was enrolled in a 1994 Aaron Diamond AIDS Research Center study of a dozen HIV-exposed individuals who remained seronegative over long periods of time.

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  • Everyone might come back seronegative, and you'd never know if it was the test or the truth was his direct quote.

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  • A patient who has tested seronegative may have a clinical presentation consistent with Lyme disease, especially if there is no evidence to indicate another illness.

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  • Last week, I was diagnosed with seronegative arthritis, in addition to the fibromyalgia.

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  • Furthermore, we observed no difference in any of the B19 infection parameters between the cells obtained from B19 seropositive and seronegative donors.

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  • Despite this intervention failure, the subgroup analysis by Celum et al. (Figure 4 of their article) indicates that the incidence of HIV-1 infection among persons who were seropositive for herpes simplex virus type 2 (HSV-2) was approximately double the incidence among persons who were seronegative for HSV-2.

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  • Prior to inoculation, all rabbits were seronegative for HEV.

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  • All control rabbits remained seronegative throughout the study.

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  • JS, Keefer M, Mulligan MJ, Schwartz D, Mestecky J, et al. (2001) A Phase I safety and immunogenicity trial of UBI microparticulate monovalent HIV-1 MN oral peptide immunogen with parenteral boost in HIV-1 seronegative human subjects.

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