Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
serpin .
Etymologies
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Examples
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Previous experience with structural biology of the serpins is highly desirable.
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• Conformational pathology of the serpins - themes, variations and therapeutic strategies.
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We have used transient transfection of COS7 cells and mouse embryonic fibroblasts, PC12 cell lines that conditionally express wild type and mutant neuroserpin and fly models of FENIB to assess the cellular handling of wild type and mutant serpins.
Journal of Biological Chemistry current issue Kroeger, H., Miranda, E., MacLeod, I., Perez, J., 2009
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These peptides are derived from members of the type IV collagen, thrombospondin, and CXC chemokine protein families, as well as somatotropin hormones, serpins, and various kringle-containing proteins.
Proceedings of the National Academy of Sciences current issue 2008
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Together our findings show that ZPI functions like other serpins to regulate the activity of FXa but in a manner uniquely dependent on protein Z, procoagulant membranes,
Journal of Biological Chemistry current issue X. Huang 2008
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Here we show that ZPI and its cofactor, protein Z (PZ), inhibit procoagulant membrane-bound factor Xa by the branched pathway acyl-intermediate trapping mechanism used by other serpins, but with significant variations of this mechanism that are unique to ZPI.
Journal of Biological Chemistry current issue X. Huang 2008
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