from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of several enzymes that act as regulatory factors that mediate the life-extending effects of a low-calorie diet.


Sorry, no etymologies found.


  • It is designed to activate a protein called sirtuin, which is believed to mimic the effects of caloric restriction.

    Glaxo Ends Study Of

  • Sirtris was formed on the premise that resveratrol could activate SIRT1, and the company's researchers set out to discover similar compounds (called sirtuin mimetics) that would be more potent activators of this possibly life-extending gene.

    Gerontology Comes of Age

  • The gene regulates the production of a class of proteins known as sirtuin one.

    Gene Shows Promise for Alzheimer's

  • This strengthens your immune cells and causes the production of a protein called sirtuin that decreases inflammation.


  • The new drugs are called sirtuin activators, meaning that they activate an enzyme called sirtuin.

    Unions and Management

  • When it comes to calorie restriction, the mechanism that slows aging comes in the formof a protein called sirtuin.

    You Staying Young

  • Resveratrol, a naturally occurring substance found in low quantities in red wine, affects many different mechanisms in the body, including a protein called sirtuin enzyme one, or Sirt1.

    Sirtris Describes Three New Drugs

  • They said that a family of proteins called sirtuin could have given the protection. - Local News

  • Add to everyone's life expectancy with "sirtuin" research or "mitochondria" research, and let the marketers name it.

    The Speculist: December 2006 Archives

  • Other scientists believe that enzymes, such as sirtuin, keep the body healthful in youth, but become less powerful with age.

    Canada Free Press


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