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sirtuin love

sirtuin

Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun Any of a family of enzymes that occur in all living organisms and are thought to regulate cellular aging, apoptosis, and resistance to stress in more complex eukaryotic organisms.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry Any of several enzymes that act as regulatory factors that mediate the life-extending effects of a low-calorie diet.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[Alteration of Sir2, name of the first gene coding for the synthesis of such enzymes to be isolated (short for s(ilent mating-type) i(nformation) r(egulation) 2, so called because the gene silences the expression of genes relating to the two mating types of the yeast from which it was isolated ) + –in.]

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Examples

  • It is designed to activate a protein called sirtuin, which is believed to mimic the effects of caloric restriction.

    Glaxo Ends Study Of Peter Loftus 2010

  • Sirtris was formed on the premise that resveratrol could activate SIRT1, and the company's researchers set out to discover similar compounds (called sirtuin mimetics) that would be more potent activators of this possibly life-extending gene.

    Gerontology Comes of Age 2010

  • The gene regulates the production of a class of proteins known as sirtuin one.

    Gene Shows Promise for Alzheimer's 2010

  • This strengthens your immune cells and causes the production of a protein called sirtuin that decreases inflammation.

    THE PROGRAM KELLY TRAVER 2009

  • This strengthens your immune cells and causes the production of a protein called sirtuin that decreases inflammation.

    THE PROGRAM KELLY TRAVER 2009

  • The new drugs are called sirtuin activators, meaning that they activate an enzyme called sirtuin.

    Unions and Management Steven Barnes 2008

  • When it comes to calorie restriction, the mechanism that slows aging comes in the formof a protein called sirtuin.

    You Staying Young MEHMET C. OZ 2007

  • When it comes to calorie restriction, the mechanism that slows aging comes in the formof a protein called sirtuin.

    You Staying Young MEHMET C. OZ 2007

  • Resveratrol, a naturally occurring substance found in low quantities in red wine, affects many different mechanisms in the body, including a protein called sirtuin enzyme one, or Sirt1.

    Sirtris Describes Three New Drugs 2007

  • When it comes to calorie restriction, the mechanism that slows aging comes in the formof a protein called sirtuin.

    You Staying Young MEHMET C. OZ 2007

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