Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A polypeptide hormone produced chiefly by the hypothalamus that inhibits the secretion of various other hormones, such as somatotropin, glucagon, insulin, thyrotropin, and gastrin.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A polypeptide hormone, secreted by the pancreas, that inhibits the production of certain other hormones.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[somato(tropin) + –stat + –in.]

from Wiktionary, Creative Commons Attribution/Share-Alike License

Ancient Greek σῶμα + statin

Examples

  • It is now commonly accepted that there are a group of peptides such as somatostatin (49, 50), substance P (51), vasoactive intestinal peptide (52) and cholecystokinin or its C-terminal octapeptide

    Nobel Lecture Radioimmunoassay: A Probe For Fine Structure Of Biologic Systems

  • Nor do the authors have good words for dairy which they write treats unwitting consumers to prolactin, somatostatin, melatonin, oxytocin, growth hormone, luteinizing hormone-releasing hormone, thyrotropin-releasing hormone, thyroid-stimulating hormone and fourteen other unwanted hormones in addition to fat, calories, cholesterol and antibiotics.

    Skinny "Bastards" and Pastors Join "Bitches" in Praising V-word

  • But then there was a seminar describing the synthesis and cloning of a gene for somatostatin.

    Kary B. Mullis - Nobel Lecture

  • My group synthesized several new classes of antitumor peptides such as LH-RH antagonists, somatostatin analogs, bombesin/GRP antagonists, GH-RH antagonists and targeted cytotoxic analogs of LH-RH, bombesin and somatostatin.

    Andrew V. Schally - Autobiography

  • My group demonstrated that the receptors for LH-RH, somatostatin and bombesin are present in various tumors, including human prostatic, mammary, endometrial and ovarian cancers.

    Andrew V. Schally - Autobiography

  • Professor S. Konturek showed that somatostatin also inhibits gastric acid and pepsin secretion, and the release of duodenal hormones, secretin and cholecystokinin.

    Andrew V. Schally - Autobiography

  • The clinical work on somatostatin was carried out mainly in England.

    Andrew V. Schally - Autobiography

  • Based on this demonstration of receptors for peptides in various tumors, I started in 1995 the development of modern cytotoxic analogs of LH-RH, bombesin and somatostatin, which can be targeted to peptide receptors on various primary cancers and their metastases.

    Andrew V. Schally - Autobiography

  • Particularly important was the establishment of a radioimmunoassay for somatostatin by Dr. Arimura.

    Andrew V. Schally - Autobiography

  • P. Brazeau and collaborators in 1973 announced the isolation and structure of ovine somatostatin, we purified this hormone from porcine hypothalami, determined its structure and synthesized it.

    Andrew V. Schally - Autobiography

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