Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A protein of high molecular weight that is a major component of the membrane of red blood cells.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A contractile protein found on the surface of the membranes of blood cells.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

spect(e)r (so called because a red blood cell without hemoglobin is called a ghost) + -in.

Examples

  • Together with Vann, I evaluated the membranes and found them to be grossly deficient in spectrin, and we reported the study in the New England Journal of Medicine.

    Peter Agre - Autobiography

  • They discovered that ATP controls binding between the fatty cell membrane and the interior cellular structure, known as the spectrin network, which is necessary for the membrane vibrations to occur.

    PhysOrg.com - latest science and technology news stories

  • Andy and I continued the spherocytosis studies, establishing that the level of spectrin deficiency correlated with the clinical severity of the disease in new reports published in Nature and the New England Journal of Medicine.

    Peter Agre - Autobiography

  • Vann had also joined the Wellcome Laboratories, and he developed techniques to study the principal structural proteins from red blood cell membranes - spectrin, which formed the girders of the membrane skeleton, and ankyrin, the attachment protein that he discovered.

    Peter Agre - Autobiography

  • A fly larva carrying a faulty human {beta} - III-spectrin gene hoists its paralyzed hindquarters, a maneuver called a tail flip.

    WN.com - Articles related to Team Finds Promising New Drug Target For Alzheimer's

  • Williams J, Klipfell E, Zarnescu D, Thomas G, et al. (2002) Crumbs interacts with moesin and beta (Heavy) - spectrin in the apical membrane skeleton of Drosophila.

    PLoS ONE Alerts: New Articles

  • The evolutionary conserved transmembrane protein Crumbs (Crb) has an influence on the organisation of the actin cytoskeleton at the apical portion of the cell through the interaction with the actin-binding factor β-heavy spectrin

    PLoS ONE Alerts: New Articles

  • They engineered fruit flies to carry a mutated {beta} - III spectrin gene from either of two human families affected with SCA5, including one descended from Abraham Lincoln's paternal grandparents (whether Lincoln himself had the disease isn't clear).

    Science Blog

  • Vesicles from flies that made the faulty {beta} - III? spectrin were slower and more likely to change direction, and thus traveled shorter distances.

    Science Blog

  • The complex containing {beta} - III? spectrin, dynactin, and dynein might not just haul cargoes.

    Science Blog

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