from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun organic chemistry The aminodiol 2-amino-1,3-octadecanediol that is a component of the sphingolipids; any homologous compound that has other that 18 carbon atoms


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  • Roff CF, Miller SPF, Rodriguez-Lafrasse C, Vanier MT, et al. (1992) Type C Niemann-Pick disease: a murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in the liver.

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  • In normal tissues free sphingoid bases (essentially sphingosine and sphinganine) are only present in minute amounts, similar to GM2 and GM3 gangliosides in the brain.

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  • Fig. 7B), as well as of free sphinganine (data not shown), in good accordance to previously published data

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