Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun organic chemistry, medicine A psychoactive drug structurally related to butyrophenone

Etymologies

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Examples

  • The Wnt inhibitory function of spiperone is not associated with its dopamine -, serotonin - and sigma-receptor antagonist properties.

    BioMed Central - Latest articles

  • The Wnt inhibitory function of spiperone is not associated with its dopamine -, serotonin - and sigma-receptor antagonist properties.

    BioMed Central - Latest articles

  • Instead, spiperone increases intracellular calcium levels in a similar manner to thapsigargin, that also impedes Wnt signal transduction.

    BioMed Central - Latest articles

  • We identified spiperone, a psychotropic drug, as a novel Wnt inhibitor, which specifically blocks canonical Wnt signaling prior to the activation of beta-catenin.

    BioMed Central - Latest articles

  • We identified spiperone, a psychotropic drug, as a novel Wnt inhibitor, which specifically blocks canonical Wnt signaling prior to the activation of beta-catenin.

    BioMed Central - Latest articles

  • Instead, spiperone increases intracellular calcium levels in a similar manner to thapsigargin, that also impedes Wnt signal transduction.

    BioMed Central - Latest articles

  • Inhibition of protein kinase C had no effect on spiperone-mediated antagonism of Wnt signaling.

    BioMed Central - Latest articles

  • Inhibition of protein kinase C had no effect on spiperone-mediated antagonism of Wnt signaling.

    BioMed Central - Latest articles

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