Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A nucleoprotein particle that aids in the splicing of messenger RNA in eukaryotes.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics A dynamic complex of RNA and protein subunits that removes introns from precursor mRNA.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[splice + –some.]

from Wiktionary, Creative Commons Attribution/Share-Alike License

splice +‎ -o- +‎ -some

Examples

  • Like a film director cutting out extraneous footage to create a blockbuster, the cellular machine called the spliceosome snips out unwanted stretches of genetic material and joins the remaining pieces to fashion a template for protein production.

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  • By molecular-scale standards, the spliceosome is a monster of a machine, made up of five RNA and 100 or more protein subunits that agilely assemble, step-by-step, into the giant complex when it's time to carry out its work.

    PhysOrg.com - latest science and technology news stories

  • The spliceosome is a ribonucleoprotein machine that removes introns from pre-mRNA in a two-step reaction.

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  • Scientists had also pinpointed how pladienolides kill cancer cells-by jamming a particular enzyme in the cancer cell's machinery, called a spliceosome, which enables the cell to edit its genetic blueprint molecule, RNA, in the replication process.

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  • Scientists had also pinpointed how pladienolides kill cancer cells-by jamming a particular enzyme in the cancer cell's machinery, called a spliceosome, which enables the cell to edit its genetic blueprint molecule, RNA, in the replication process.

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  • Scientists had also pinpointed how pladienolides kill cancer cells-by jamming a particular enzyme in the cancer cell's machinery, called a spliceosome, which enables the cell to edit its genetic blueprint molecule, RNA, in the replication process.

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  • Scientists had also pinpointed how pladienolides kill cancer cells-by jamming a particular enzyme in the cancer cell's machinery, called a spliceosome, which enables the cell to edit its genetic blueprint molecule, RNA, in the replication process.

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  • Scientists had also pinpointed how pladienolides kill cancer cells-by jamming a particular enzyme in the cancer cell's machinery, called a spliceosome, which enables the cell to edit its genetic blueprint molecule, RNA, in the replication process.

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  • Scientists had also pinpointed how pladienolides kill cancer cells-by jamming a particular enzyme in the cancer cell's machinery, called a spliceosome, which enables the cell to edit its genetic blueprint molecule, RNA, in the replication process.

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  • Scientists had also pinpointed how pladienolides kill cancer cells-by jamming a particular enzyme in the cancer cell's machinery, called a spliceosome, which enables the cell to edit its genetic blueprint molecule, RNA, in the replication process.

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