spongiosis

The brains of these mice had classic signs of prion disease, including microscopic holes, called spongiosis, throughout the brain.

PhysOrg.com - latest science and technology news stories 2010

The brains of these mice had classic signs of prion disease, including microscopic holes, called spongiosis, throughout the brain.

Medlogs - Recent stories 2010

We demonstrate that skin-specific inactivation of Notch1 and Notch2 simultaneously, or RBP-J, induces the development of a severe form of atopic dermatitis (AD), characterized by acanthosis, spongiosis and hyperkeratosis, as well as a massive dermal infiltration of eosinophils and mast cells.

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

We demonstrate that skin-specific inactivation of Notch1 and Notch2 simultaneously, or RBP-J, induces the development of a severe form of atopic dermatitis (AD), characterized by acanthosis, spongiosis and hyperkeratosis, as well as a massive dermal infiltration of eosinophils and mast cells.

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

Asterisks indicate enlarged regions of the skin showing acanthosis, hyperkeratosis and spongiosis of the epidermis as well as eosinophil infiltrates (arrows) around dilated blood vessels (bv) in the dermis (n = 8, 4 individual experiments were performed).

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

Notch mutant mice lacking TSLPR have a markedly less proliferative epidermis, do not develop spongiosis and have large a reduction in dermal inflammatory cells (arrows, n = 6 per sample group, three individual experiments).

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

H/E and Toluidin blue staining shows acanthosis, hyperkeratosis, spongiosis, epidermoid cysts and massive infiltration of mast cells in the dermis of the N1N2K5 derived graft.

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

E) Goldner's Trichrome (GT) readily shows the spongiosis and hyperkeratosis (n = 7, 4 individual experiments were performed).

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

Additional loss of TSLPR led to a markedly less proliferative epidermis, which was also devoid of spongiosis and displayed a substantial decrease in inflammatory dermal infiltrates compared to N1N2K5 animals (

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

Figure 1D, E) and RBP-JK5 (data not shown) mice showed signs of intercellular oedema (epidermal spongiosis).

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010