Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun medicine An alkaloid derived from the bacterium Streptomyces staurosporeus that has antifungal and antihypertensive activity

Etymologies

Sorry, no etymologies found.

Examples

  • In 1976, a team of Japanese researchers looking for poisons in sea bacteria had accidentally discovered a molecule called staurosporine, a large molecule shaped like a lopsided Maltese cross that bound to a pocket present in most kinases.

    The Emperor of All Maladies

  • In 1976, a team of Japanese researchers looking for poisons in sea bacteria had accidentally discovered a molecule called staurosporine, a large molecule shaped like a lopsided Maltese cross that bound to a pocket present in most kinases.

    The Emperor of All Maladies

  • In 1976, a team of Japanese researchers looking for poisons in sea bacteria had accidentally discovered a molecule called staurosporine, a large molecule shaped like a lopsided Maltese cross that bound to a pocket present in most kinases.

    The Emperor of All Maladies

  • Unlike staurosporine, though, this skeletal structure was a much simpler chemical.

    The Emperor of All Maladies

  • Unlike staurosporine, though, this skeletal structure was a much simpler chemical.

    The Emperor of All Maladies

  • Unlike staurosporine, though, this skeletal structure was a much simpler chemical.

    The Emperor of All Maladies

  • RGC5 cells were transfected with pOPTN-EGFP for 20 h and underwent differentiation with treatment of 316 nM staurosporine for 4 h.

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  • In some experiments, RGC5 cells were differentiated with 316 nM staurosporine for 4 h [39].

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  • In this study, we found that jun N-terminal kinase (JNK) was activated in etoposide - and staurosporine-treated, but not serum-starved, Bax

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  • Nevertheless, they did stain positively for neuronal markers β-tubulin and PGP9. 5, as well as for the microtubule-associated protein, tau, and were able to differentiate with neurite extensions after treatment of staurosporine, suggesting that these cells still represent neuronal precursor cells.

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