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suberoylanilide

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The anilide of suberic acid

Etymologies

Sorry, no etymologies found.

Examples

  • The new study, performed in collaboration with a large number of cystic fibrosis investigators across the United States and Canada, showed that a compound called suberoylanilide hydroxamic acid (SAHA), which is already approved by the U.S.

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  • The study, performed in collaboration with cystic fibrosis investigators across the United States and Canada, showed a compound called suberoylanilide hydroxamic acid, known as SAHA, can restore about 28 percent of normal function to lung surface cells with the most common, but most severe, cystic fibrosis mutation, researchers said.

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  • Injections of sodium valproate, sodium butyrate, or vorinostat (suberoylanilide hydroxamic acid; Zolinza┬«) completely restored contextual memory in these mutant mice.

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  • Pancani T, Formentini L, Mascagni P, Fossati G, et al. (2006) Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse brain.

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  • For experiments involving suberoylanilide hydroxamic acid (SAHA), the drug was prepared as a 100 mg/ml stock in DMSO.

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  • These behavioral improvements were not observed when SAHA (suberoylanilide hydroxamic acid), a selective HDAC inhibitor, was administered.

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  • The drug suberoylanilide hydroxamic acid (SAHA), originally used to treat lymphoma, was able to restore

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  • Pranpat M, Swaby R, Fiskus W, Yamaguchi H, et al. (2005) Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2.

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  • In lung cells from CF patients, low doses of one inhibitor, suberoylanilide hydroxamic acid (SAHA), already an FDA-approved drug for cancer, gradually restored about 28% of normal channel function and kept it there for up to 10 days after treatment.

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  • (suberoylanilide hydroxamic acid), a selective HDAC inhibitor, was administered.

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