Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Underneath the retina

from The Century Dictionary and Cyclopedia

  • Lying beneath the retina.

Etymologies

sub- +‎ retinal (Wiktionary)

Examples

  • Detachment of the retina may occur, often preceded by or accompanied by subretinal hemorrhage.

    Glaucoma A Symposium Presented at a Meeting of the Chicago Ophthalmological Society, November 17, 1913

  • Wang S, Lund RD (2005) Time course of deterioration of rod and cone function in RCS rat and the effects of subretinal cell grafting: a light - and dark-adaptation study.

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  • In comparison, subretinal delivery of cells including bone marrow derived cells

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  • Hauswirth WW, Aleman TS, Kaushal S, Cideciyan AV, Schwartz SB, et al. (2008) Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial.

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  • An advantage of delivering donor cells via subretinal injection method is that the therapeutic material is placed directly in the space where the defective RPE cells or degenerating photoreceptors are targeted, and in this fashion both photoreceptors and visual function can be partially preserved

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  • One patient was so thrilled with the results, the company added, that he refused to have the implants removed after the study's one - or three-month testing period, and he reports continued success four years later. subretinal implants, it described in a statement, place the chip in the macular region, beneath the retina:

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  • /5 (AAV2 /5), and delivered via subretinal injection to the normal canine retina.

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  • Immunofluorescence examination of F4/80 expression in mouse retinas following subretinal delivery of compacted DNA nanoparticles or saline.

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  • In this study we show that the CK30PEG-compacted DNA nanoparticles containing a CMV-EGFP expression vector are non-toxic and well-tolerated in the murine eye after subretinal injection.

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  • Previous promising results have come from delivery of CK30PEG compacted DNA nanoparticles to the subretinal space

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