Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun An extracellular enzyme produced by certain strains of a soil bacterium (Bacillus amyloliquefaciens) that catalyzes the breakdown of proteins into polypeptides and resembles trypsin in its action.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A protease produced by soil bacteria of the genus Bacillus

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[New Latin (Bacillus) subtīlis, bacteria species; see subtilin + –in.]

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Examples

  • P. dendritiformis also secretes a protein called subtilisin, which promotes growth, except in high concentrations.

    PhysOrg.com - latest science and technology news stories 2010

  • Bacteria use the enzyme, called subtilisin, as a sort of food processor: After producing it internally, they release the enzyme into the soil, where it uses a minuscule "blade" to chop up proteins into digestible pieces.

    THE MEDICAL NEWS 2009

  • Bacteria use the enzyme, called subtilisin, as a sort of food processor: After producing it internally, they release the enzyme into the soil, where it uses a minuscule "blade" to chop up proteins into digestible pieces.

    EurekAlert! - Breaking News 2009

  • Bacteria use the enzyme, called subtilisin, as a sort of food processor: After producing it internally, they release the enzyme into the soil, where it uses a minuscule "blade" to chop up proteins into digestible pieces.

    innovations-report 2009

  • Bacteria use the enzyme, called subtilisin, as a sort of food processor: After producing it internally, they release the enzyme into the soil, where it uses a minuscule "blade" to chop up proteins into digestible pieces.

    THE MEDICAL NEWS 2009

  • HOERSHOLM, Denmark and SAN DIEGO, April 26 Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies, today announced that it has advanced into drug development a discovery research candidate directed against PCSK9 (proprotein convertase subtilisin/kexin type 9), an important new target for the treatment of high cholesterol.

    Medindia Health News 2010

  • HOERSHOLM, Denmark and SAN DIEGO, April 26 Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies, today announced that it has advanced into drug development a discovery research candidate directed against PCSK9 (proprotein convertase subtilisin/kexin type 9), an important new target for the treatment of high cholesterol.

    Medindia Health News 2010

  • Alnylam has an ongoing development program focused on using RNAi therapeutics targeting proprotein convertase subtilisin/kexin type 9, or PCSK9, as a novel strategy for reducing LDL (or "bad") cholesterol.

    FinanzNachrichten.de: Aktuelle Nachrichten 2010

  • Nakayama K (1997) Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins.

    PLoS ONE Alerts: New Articles Katarina Hajdin et al. 2010

  • Proprotein convertases (PC) are a family of subtilisin-like serine proteases.

    PLoS ONE Alerts: New Articles Katarina Hajdin et al. 2010

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