suprabasal

Confinement of PPARβ/δ transgene expression to suprabasal epidermal keratinocytes.

PLoS ONE Alerts: New Articles Malgorzata Romanowska et al. 2010

B. Nuclear accumulation of PPARβ/δ in suprabasal epidermis in psoriasis skin lesions.

PLoS ONE Alerts: New Articles Malgorzata Romanowska et al. 2010

To model the suprabasal expression of PPARβ/δ observed in psoriasis in humans, we initially intended to target transgenic PPARβ/δ expression using a "conventional" promoter active in suprabasal epidermis, e.g. the involucrin promoter.

PLoS ONE Alerts: New Articles Malgorzata Romanowska et al. 2010

In normal human epidermis, relatively low levels of TGF-β1 are expressed predominantly in the suprabasal, differentiating layers, suggesting it may have a role in maintaining the cessation of growth in the differentiating cells of epidermis During re-epithelialisation, the expression of TGF-β1 is induced by various ECM components.

PLoS ONE Alerts: New Articles Salem Adra et al. 2010

We show that human AD patients have reduced Notch receptor levels on the cell surface of the suprabasal epithelium and they are known to have an increased risk to develop hematological malignancies

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

Compared to controls, samples treated with repeated doses of DUVR showed drastic alterations in epidermis (decreased thickness and death of suprabasal keratinocytes) and dermis (decrease in the number of fibroblasts).

PLoS ONE Alerts: New Articles Claire Marionnet et al. 2010

Targeting PPARβ/δ expression to suprabasal skin in mice in vivo

PLoS ONE Alerts: New Articles Malgorzata Romanowska et al. 2010

Notch receptors are expressed in the suprabasal cell layer of the skin.

PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

Immunohistochemical analysis revealed aberrant suprabasal Cldn localization with marked down-regulation of Cldn1.

PLoS ONE Alerts: New Articles Tammy-Claire Troy et al. 2009

Sporadic Cldn1-positive basal cells were evident in the 2-week old transgenic epidermis; by 1-month of age Cldn1-positive cells occupied both the basal and suprabasal compartments reminiscent of the wild type.

PLoS ONE Alerts: New Articles Tammy-Claire Troy et al. 2009