Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A drug used to treat onchocerciasis and human sleeping sickness caused by trypanosomes

Etymologies

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Examples

  • Diethylcarbamazine and suramin are other medicines used to treat river blindness, but these can sometimes do more harm than good, especially when eye damage has already begun.

    Chapter 23 1993

  • If ivermectin is not available, an experienced health worker can give diethylcarbamazine first and then also suramin.

    Chapter 31 1993

  • For adults inject 1 gm. of suramin in 10 ml. of distilled water once a week for 5 to 7 weeks.

    Chapter 31 1993

  • The results explain the marked species difference in antagonist sensitivity and identify an ectodomain lysine residue that plays a key role in the binding of both suramin and NF449 to P2X1 receptors.

    Journal of Biological Chemistry current issue J. A. Sim 2008

  • Conversely, when lysine was introduced into the mouse receptor, the sensitivity to block by suramin and NF449 was much increased for E138K, but not for Q111K, Q127K, or N148K.

    Journal of Biological Chemistry current issue J. A. Sim 2008

  • The substitution K138E, either alone or together with K111Q, K127Q, and K148N, reduced the sensitivity to block by both suramin and NF449.

    Journal of Biological Chemistry current issue J. A. Sim 2008

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