Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A particular
tubulin -binding drug, asynthetic derivative of dolastatin.
Etymologies
Sorry, no etymologies found.
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Examples
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Genzyme says tasidotin, a dolastatin analogue, has a unique mechanism of action that appears to differ from other microtubule stabilizers such as taxanes and epothilones as well as tubulin inhibitors such as Vinca alkaloids.
GEN News Highlights 2009
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In an earlier Phase II clinical trial sponsored by Genzyme, the intravenous formulation of tasidotin demonstrated clinical activity in patients with melanoma.
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FRANKFURT, GERMANY -- (MARKET WIRE) -- May 6, 2009 -- Ergomed announced today that it has signed an agreement with Genzyme Corporation on the co-development of tasidotin, a novel dolastatin analogue that has shown efficacy signals and a good safety profile in previous oncology clinical trials.
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"We are pleased to be advancing the tasidotin development program with Ergomed as our partner," said Mark Enyedy, president of Genzyme Oncology and Multiple Sclerosis.
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Ergomed, for co-development of tasidotin, Genzyme's anticancer candidate.
GEN News Highlights 2009
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As part of the collaboration agreement Ergomed will move the oral formulation of tasidotin, developed by Genzyme, into clinical trials.
GEN News Highlights 2009
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FRANKFURT, GERMANY -- (MARKET WIRE) -- May 6, 2009 -- Ergomed announced today that it has signed an agreement with Genzyme Corporation on the co-development of tasidotin, a novel dolastatin analogue that has shown efficacy signals and a good safety profile in previous oncology clinical trials.
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Ergomed, for co-development of tasidotin, Genzyme's anticancer candidate.
GEN News Highlights 2009
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As part of the agreement, Ergomed will advance the oral formulation of tasidotin, developed by Genzyme, into clinical trials.
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A previous, Genzyme-sponsored Phase II trial with an intravenous formulation of tasidotin demonstrated clinical activity in melanoma patients.
GEN News Highlights 2009
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