Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A particular
antiangiogenic drug .
Etymologies
Sorry, no etymologies found.
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Examples
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A blood vessel-blocking drug called tasquinimod slowed the rate of disease progression in a clinical trial of 200 prostate cancer patients, according to experts at Johns Hopkins, Roswell Park Cancer Institute and Duke University.
PhysOrg.com - latest science and technology news stories 2010
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Funding for the study was provided by Active Biotech, manufacturer of tasquinimod, and the
PhysOrg.com - latest science and technology news stories 2010
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However, the drug's cardiac side effects were too toxic for humans, so Isaacs in collaboration with the pharmaceutical company Active Biotech identified tasquinimod for clinical testing after searching for drugs similar to linomide with the same blood vessel action but with less toxicity.
PhysOrg.com - latest science and technology news stories 2010
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Research leading to tasquinimod began in the early 1990s when John Isaacs, Ph. D., professor at the Johns Hopkins Kimmel Cancer Center, found that a drug called linomide, which had been tested in multiple sclerosis, restricted blood supply to prostate tumors.
PhysOrg.com - latest science and technology news stories 2010
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Isaacs says that tasquinimod works by stopping new blood vessel development around the tumor, but does not make existing vasculature disappear.
PhysOrg.com - latest science and technology news stories 2010
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At six months, 57 percent of men taking tasquinimod had no disease progression as compared with 33 percent taking a placebo.
PhysOrg.com - latest science and technology news stories 2010
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At six months, 57% of men taking tasquinimod had no disease progression as compared with
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