from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. any of a class of diterpenoid drugs that inhibit cancer cell growth and division. Examples are Paclitaxel (taxol) and Docetaxel (taxotere).


from Wiktionary, Creative Commons Attribution/Share-Alike License

Scientific Latin Taxus ("yew") +‎ -ane


  • The compound works in much the same way as the taxane drugs, including Taxol, which were originally derived from Pacific yew trees.

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  • Therapy using a combination of drugs—especially the combinations called CA (cyclophosphamide and adriamycin) and a taxane (taxol or taxotere)—gave better results in studies than one drug used alone.


  • Medical Oncology ESMO in October 2010 showed that after six months, patients on T-DM1 had an overall response rate of 48% compared to 41% for Herceptin plus a taxane.

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  • This study will evaluate the investigational drug farletuzumab, given in combination with carboplatin and taxane, for women with relapsed platinum-sensitive epithelial ovarian cancer.

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  • Meg McArthur, senior policy officer at Breakthrough Breast Cancer, said: We are disappointed with NICE's final decision not to approve Avastin with a taxane.

    BBC News - Home

  • Proceeds of the financing will be used to accelerate development of the Company's small molecule pipeline, particularly late-stage registration studies of tesetaxel, the leading oral taxane in clinical development.

  • As the leading oral taxane in clinical development, tesetaxel has been evaluated in a broad program of completed or ongoing Phase 2a/Phase 2b clinical trials.

  • The Company is developing tesetaxel, a novel, orally absorbed taxane that is in the same class of drugs as paclitaxel and docetaxel.

  • Among the patients who responded to treatment with GRN1005, were patients who had previously progressed on taxane therapy.

    Reuters: Press Release

  • Sultan said the research team focused on the OVCAR-3 cell line, which was one of the highest SYK-expressing cell lines, to elucidate the potential effects of SYK on taxane sensitivity.

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