Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of a class of glycoprotein found in the extracellular matrix of developing vertebrate embryos

Etymologies

Sorry, no etymologies found.

Examples

  • That target is an immune system compound called tenascin-C.

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  • TGF-β1 also regulates the behaviour of keratinocytes by inducing the expression of various ECM proteins such as tenascin, thrombospondin, fibronectin, vitronectin, collagen and several proteoglycans etc.

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  • Whitby DJ, Longaker MT, Adzick NS, Harrison MR, Ferguson MWJ: Rapid epithelialization of fetal wounds is associated with the early deposition of tenascin.

    CHOP scarless fetal wound healing publications

  • These include well-established adhesion molecules and receptors such as brevican, tenascin C, integrin αv, and dystroglycan-1, some of which are critical for structural integrity of the glial scaffold

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  • Recent studies also showed that the expression of tenascin-C in invasion borders of early breast cancer significantly correlates with proliferative activity, higher risk of distant metastasis and local recurrence

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  • To investigate the regulation of Beclin 1 by 14-3-3τ in a physiological context, we made use of an extracellular matrix protein tenascin-C, which has been reported to induce 14-3-3τ in

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  • The regulation is physiologically relevant as an extracellular matrix protein tenascin-C, a known 14-3-3τ inducer, can induce Beclin 1 through 14-3-3τ.

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  • As shown in Figure 2A-B, tenascin-C induced 14-3-3τ and Beclin 1 when compared with fibronectin control, and the induction of Beclin 1 was blocked when 14-3-3τ was depleted.

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  • These results indicate that the induction of Beclin 1 by tenascin-C is mediated through 14-3-3τ.

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  • We therefore hypothesized that tenascin-C might regulate Beclin 1 through 14-3-3τ.

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