from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun An antihistamine drug formerly used to treat allergic conditions, superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia.


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  • Stop adding antifungal medications sporanox nizoral and appear your terbinafine at slowly if you have runny or being terfenadine pain, or if you eliminate light-headed.


  • Furthermore, experts argue that if the health ministry could in the past ban painkiller rofecoxib, diabetes drug phenformin, and anti-allergy drugs astemizole and terfenadine due to adverse effects based on global reports, why can't the same logic be applied in case of other drugs which have been banned globally?

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  • In drug-interaction studies, the recommended clinical dose of montelukast did not have clinically important effects on the pharmacokinetics of the following drugs: theophylline, prednisone, prednisolone, oral contraceptives (norethindrone 1 mg / ethinyl estradiol 35 mcg), terfenadine, digoxin, and warfarin.

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  • Recognition and reporting of this arrhythmia in association with terfenadine, astemizole (Hismanal), cisapride (Propulsid), grepafloxacin (Raxar), and mibefradil (Posicor) ultimately led to the removal of these medications from the market.

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  • • did not change the plasma concentration profile of terfenadine (a substrate of CYP 3A4) or fexofenadine, its carboxylated metabolite, and did not prolong the QTc interval following co-administration with terfenadine 60 mg twice daily.

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