Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun The active metabolite of leflunomide.

Etymologies

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Examples

  • The study showed teriflunomide also reduced disability progression by 30% and 24%, depending on the dose, Sanofi said.

    Sanofi Says MS Drug Reduces Relapses Mimosa Spencer 2010

  • Smaller reductions in flare-ups were seen in trials with patients using laquinimod (23%) and teriflunomide (31%).

    Pills Offer Easier Way to Treat MS Thomas Gryta 2011

  • Recent data from large clinical trials of other drugs being developed, including Biogen Idec's BG-12, Teva Pharmaceutical's laquinimod, and teriflunomide, from Sanofi-Aventis SA, show they are also effective at controlling MS flare-ups and slowing the progression of disability from the disease.

    Pills Offer Easier Way to Treat MS Thomas Gryta 2011

  • PARIS — French pharmaceutical giant Sanofi-Aventis said Friday a two-year phase III study of its multiple-sclerosis drug teriflunomide reduced the relapse rate of patients by 31%.

    Sanofi Says MS Drug Reduces Relapses Mimosa Spencer 2010

  • Separately, French drug maker Sanofi SA said a drug it is developing for multiple sclerosis, teriflunomide, failed to prove more effective than an older MS drug in a trial in 324 patients.

    AstraZeneca, Novartis Report Drug Setbacks Jeanne Whalen 2011

  • France's Sanofi-Aventis SA, meanwhile, is carrying out large clinical trials of an oral MS drug called teriflunomide.

    Novartis's MS Drug Wins U.S. Approval 2010

  • French drugmaker Sanofi says its multiple sclerosis drug candidate teriflunomide did not achieve one of its goals in a late-stage clinical trial.

    The Seattle Times 2011

  • The monotherapy program of teriflunomide progress as planned with the two Phase III trials ongoing, TOWER (versus placebo) and TENERE (versus IFN-beta 1a).

    unknown title 2011

  • Throughout 2011, further newsflow from R&D is expected with Phase III studies expected to be completed/reported for five compounds currently in development lixisenatide, teriflunomide, aflibercept, ombrabulin, and semuloparin.

    unknown title 2011

  • Sanofi said teriflunomide, also known by the trade name Aubagio, worked no better than an older drug, Rebif, in preventing relapses, as the study found "no statistical superiority" between Rebif and either 7 mg or 14 mg doses of teriflunomide.

    The Seattle Times 2011

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