from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A particular drug used in chemotherapy.


Sorry, no etymologies found.


  • As the leading oral taxane in clinical development, tesetaxel has been evaluated in a broad program of completed or ongoing Phase 2a/Phase 2b clinical trials.

  • Proceeds expected to enable initiation of global registration studies for tesetaxel

  • Proceeds of the financing will be used to accelerate development of the Company's small molecule pipeline, particularly late-stage registration studies of tesetaxel, the leading oral taxane in clinical development.

  • Key projects include finalization of regulatory review for pivotal studies of tesetaxel and selection of a lead compound for IND filing from the oral gallium portfolio.

  • The Company is developing tesetaxel, a novel, orally absorbed taxane that is in the same class of drugs as paclitaxel and docetaxel.

  • Genta has initiated a broad clinical program to evaluate the safety and efficacy of tesetaxel in patients with solid tumors.


  • The Company is also developing tesetaxel, a novel, orally absorbed, semi-synthetic taxane that is in the same class of drugs as paclitaxel and docetaxel.


  • As a late Phase 2 oncology product, tesetaxel has demonstrated anticancer activity in its initial clinical trials, and the drug has not been associated with the severe infusion reactions that are linked with conventional taxanes.


  • In developing the trial, the Company completed a dose-ranging and pharmacokinetic study of tesetaxel plus capecitabine (Xeloda (R); Hoffmann LaRoche, Inc.).


  • Based on promising results in a Phase 2a trial, Genta is conducting a confirmatory Phase 2b trial of tesetaxel as 2nd-line treatment in patients with advanced gastric cancer who have failed a single 1st-line regimen.



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