tetramerization love



from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. polymerization to form a tetramer


Sorry, no etymologies found.


  • But because GFP at least didn't have a tetramerization or severe dimerization problem – it only has a very mild one – that sort of got people hooked on what a wonderful tool this whole system was.

    Roger Y. Tsien - Interview

  • So we were more able to cope with the tetramerization when it came up a few years later.

    Roger Y. Tsien - Interview

  • They also uncovered that S100 proteins, in addition to their established binding of p53 at the tetramerization domain, could also bind p53 at the transactivation domain.

    Journal of Biological Chemistry current issue

  • Cloutier SM, Couty S, Terskikh A, Marguerat L, Crivelli V, et al. (2000) Streptabody, a high avidity molecule made by tetramerization of in vivo biotinylated, phage display-selected scFv fragments on streptavidin.

    PLoS ONE Alerts: New Articles

  • In its active form, p53 protein is a tetramer, that is to say it is formed by four identical copies of proteins bound together, which has four domains with differentiated functions: activation of transcription, DNA binding, tetramerization and regulation.

    Medlogs - Recent stories

  • The tetramerization domain is responsible for stabilizing the tetrameric structure.

    Medlogs - Recent stories

  • Although most of these are located in the DNA binding domain, several mutations are found in the tetramerization domain, thereby causing destabilization of the entire protein with the consequent loss of activity.

    EurekAlert! - Breaking News

  • Through the combination of several techniques, including nuclear magnetic resonance, the researchers have been able to describe in detail the interaction of the new compound with the tetramerization domain.

    Medlogs - Recent stories

  • Therefore, the design of compounds with the capacity to stabilize the tetramerization domain of p53 represents a new and attractive strategy for the development of anti-tumour drugs.

    Medlogs - Recent stories

  • The article describes the design, synthesis and study of a compound with the capacity to interact with the p53 tetramerization domain.

    EurekAlert! - Breaking News


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