thienopyridine love

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of a class of drugs, having a structure based on a thiophene ring fused to one of tetrahydropyridine, that have anti-platelet activity

Etymologies

Sorry, no etymologies found.

Examples

  • One difference that may turn out to be key is that patients enrolled in ATLAS ACS were stratified based upon whether the investigator planned to give aspirin alone or aspirin plus a thienopyridine such as clopidogrel or prasugrel.

  • Researchers say patients should be considered on a case-by-case basis, but at least in patients where bleeding concerns do not outweigh those for stent thrombosis, short-term discontinuation of thienopyridine therapy "may be relatively safe."

    theHeart.org

  • On February 3, 2009, the FDA's Cardiovascular and Renal Drugs Advisory Committee unanimously voted to recommend approval of the novel thienopyridine prasugrel for use in ACS patients undergoing PCI.

    theHeart.org

  • Five-to-10 day cessation of thienopyridine likely safe for surgery if aspirin maintained, post-DES

    theHeart.org

  • "When the new thienopyridine, prasugrel, is available, I would predict that most physicians will administer it to patients believed to be allergic to clopidogrel," Berger added.

    theHeart.org

  • Sanofi then synthesized and evaluated several hundred additional thienopyridine derivatives, including a class of compounds having the following general structure, wherein one of the hydrogen atoms on the bridge carbon atom (marked with an asterisk), is replaced with an ester, carboxylic acid, or amide group.

    Patent Baristas

  • Those with the CYP2C19*2 genotype may benefit more from an antiplatelet regimen that does not include clopidogrel, such as the third-generation thienopyridine prasugrel, or ticagrelor and cangrelor.

    EurekAlert! - Breaking News

  • Dual Antiplatelet Therapy: Dueling Options in Real-World Practice With the recent approval of a third-generation thienopyridine, choice of agent can be added to the list of considerations in the management of ACS patients, as well as the appropriate timing and dosing of thienopyridine.

    theHeart.org

  • As the standard of care differs across countries, the safety and efficacy of rivaroxaban was investigated on top of aspirin, or aspirin plus a thienopyridine versus placebo in a broad patient population.

    WebWire | Recent Headlines

  • The data will report the results from the ATLAS ACS TIMI 46 trial (Anti-Xa Therapy to Lower cardiovascular events in addition to aspirin with / without thienopyridine therapy in patients with Acute coronary Syndrome), a large phase II dose-finding study for secondary prevention of ACS in patients with recent ACS, chaired by Prof. Eugene Braunwald from Harvard University,

    WebWire | Recent Headlines

Comments

Log in or sign up to get involved in the conversation. It's quick and easy.