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- n. A thiolactone antibiotic active against mycobacteria
Sorry, no etymologies found.
Slayden RA, Lee RE, Armour JW, Cooper AM, Orme IM, et al. (1996) Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.
Mycolic acid biosynthesis is essential for mycobacterial survival and many antituberculosis drugs like isoniazid, ethionamide and thiolactomycin target enzymes of this exclusive pathway
M. smegmatis with thiolactomycin (TLM), a known inhibitor of KasA and KasB (