thiolactomycin love


from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun medicine A thiolactone antibiotic active against mycobacteria


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  • Slayden RA, Lee RE, Armour JW, Cooper AM, Orme IM, et al. (1996) Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.

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  • Mycolic acid biosynthesis is essential for mycobacterial survival and many antituberculosis drugs like isoniazid, ethionamide and thiolactomycin target enzymes of this exclusive pathway

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  • M. smegmatis with thiolactomycin (TLM), a known inhibitor of KasA and KasB (

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