from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of a family of antioxidant proteins that are found in all mammalian cells


Sorry, no etymologies found.


  • Selenium: A trace mineral that is a cofactor for production of active antioxidant enzymes such as glutathione peroxidases and thioredoxin reductase.

    You Staying Young

  • GSSG inhibition was a problem with thioredoxin and thioredoxin reductase which were needed to keep something in the reduced state.

    Tim Hunt - Autobiography

  • DUVR did not alter mRNA level of catalase, thioredoxin, glutathion peroxidase, or the transcription factor Nrf2 and its modulators Keap1 and Bach1.

    PLoS ONE Alerts: New Articles

  • Little is known regarding the genomic structure of flatworm TGRs, the expression of TGR variants and whether the absence of conventional thioredoxin and glutathione systems is a signature of the entire platyhelminth phylum.

    BioMed Central - Latest articles

  • In contrast to their mammalian hosts, platyhelminth (flatworm) parasites studied so far, lack conventional thioredoxin and glutathione systems.

    BioMed Central - Latest articles

  • Our results indicate that thioredoxin and glutathione pathways differ in parasitic and free-living flatworms and that canonical enzymes were specifically lost in the parasitic lineage.

    BioMed Central - Latest articles

  • Instead, they possess a linked thioredoxin-glutathione system with a selenocysteine-containing enzyme thioredoxin glutathione reductase (TGR) as the single redox hub that controls the overall redox homeostasis.

    BioMed Central - Latest articles

  • We examine platyhelminth genomes and transcriptomes and find that all platyhelminth parasites (from classes Cestoda and Trematoda) conform to a biochemical scenario involving, exclusively, a selenium-dependent linked thioredoxin-glutathione system having TGR as a central redox hub.

    BioMed Central - Latest articles

  • In contrast, the free-living platyhelminth Schmidtea mediterranea (Class Turbellaria) possesses conventional and linked thioredoxin and glutathione systems.

    BioMed Central - Latest articles

  • The thioredoxin and/or glutathione pathways occur in all organisms.

    BioMed Central - Latest articles


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