from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A protease in blood that facilitates blood clotting by converting fibrinogen to fibrin.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An enzyme in blood that facilitates blood clotting by converting fibrinogen to fibrin (by means of ionized calcium).

from the GNU version of the Collaborative International Dictionary of English

  • n. The enzyme which converts fibrinogen into fibrin.

from The Century Dictionary and Cyclopedia

  • n. The fibrin ferment which causes the coagulation of the blood; thrombase.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. an enzyme that acts on fibrinogen in blood causing it to clot


Sorry, no etymologies found.


  • In its natural state, the aptamer binds with an enzyme called thrombin, which regulates blood clotting.

    University of Florida News

  • The newer drug works on one protein in the coagulation cascade called thrombin - "which is right at the blood clot, the one right at the end of this process," Sharma says. Top Stories

  • Scientists have known that a protein called thrombin plays an important role in clot formation as a potent activator of platelets.


  • One, Pradaxa, a so-called direct thrombin inhibitor, was approved late last year by the U.S. Food and Drug Administration.

    Merck Returns Betrixaban Rights Amid Pipeline Review

  • Known as a direct thrombin inhibitor, it was superior to and safer than warfarin at one dose but a trend toward a survival benefit in a major study wasn't statistically significant.

    Study Gives Lift to Drug That Cuts Stroke Risk

  • But even with aggressive antiplatelet therapy, more than 10% of treated patients suffer heart attacks, prompting a quest to develop anticoagulants to fight another major contributor to clots: the enzyme thrombin.

    J&J Drug May Have New Role

  • Pradaxa acts by inhibiting thrombin, an enzyme in the blood that is involved in blood clotting.

    Drug to Prevent Stroke Is Approved

  • Angiotech enters license, distribution and supply agreements for fibrin and thrombin technologies with Haemacure Corporation.

    Will NYTimes Science Stoop To Propaganda?

  • Platelet aggregation and fibrin formation both require the proteolytic enzyme thrombin, plus calcium ions and about a dozen other protein clotting factors.

    It's Always about the Blood

  • Another Factor Xa inhibitor,apixaban, is in trials as is a direct thrombin inhibitor,dabigatran.

    Archive 2008-06-01


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