Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A particular synthetic thymosin used as an immunomodulator.

Etymologies

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Examples

  • ZADAXIN, scientifically referred to as thymalfasin or thymosin alpha 1, is SciClone's synthetic preparation of thymalfasin, a peptide produced by the thymus gland which circulates in the blood naturally and is instrumental in immune responses.

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  • ZADAXIN, scientifically referred to as thymalfasin or thymosin alpha 1, is SciClone's synthetic preparation of thymalfasin, a peptide produced by the thymus gland which circulates in the blood naturally, and is instrumental in the immune response to certain cancers and viral infections.

    BioSpace.com Featured News and Stories

  • SciClone's ZADAXIN® (thymalfasin) is approved in over 30 countries for the treatment of hepatitis B (HBV), hepatitis C (HCV), as a vaccine adjuvant, and certain cancers.

  • SciClone's Zadaxin (thymalfasin or thymosin alpha 1) is sold in over 30 countries for the treatment of hepatitis B (HBV) and hepatitis C (HCV), certain cancers and as a vaccine adjuvant.

    DWS Pill Scribe

  • SciClone's development pipeline of drug candidates includes thymalfasin, in clinical studies as an enhancer of vaccines; thymalfasin for stage IV melanoma, for which SciClone has reached agreement with US FDA on the design of a phase 3 trial.

    DWS Pill Scribe

  • Published scientific and clinical studies have shown that thymalfasin helps stimulate and direct the body's immune system to improve response to vaccines, and to eradicate infectious diseases like HCV and HBV, as well as certain cancers.

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  • The increase in production of antibodies after thymalfasin treatment leads to an increase in response to vaccines, providing enhanced protection against infection; the increases in T-helper cells allows the immune system to tag and identify invasive agents and cancerous cells for removal.

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  • The other groups received thymalfasin at either a low dose (3.2 mg) or a high dose (6.4 mg).

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  • Within the immune system, thymalfasin stimulates stem cell differentiation and increases production of antibodies and disease-fighting T cells, including CD4, CD8, and natural killer cells, while simultaneously slowing the breakdown and removal of these T cells.

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  • The mice in the study were treated with thymosin alpha 1 (Talpha1/thymalfasin), a synthetic form of the hormone thymosin, produced by the thymus gland.

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