Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any salt or ester of thymidylic acid

Etymologies

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Examples

  • The proprietary ResponseDX ™ panels include four key genes: excision repair cross-complementing factor 1 (ERCC1), thymidylate synthase (TS), human epidermal growth factor receptor 2 (HER2) and epidermal growth factor receptor (EGFR) expression.

    Business Wire Travel News

  • ONX 0801, an alpha-folate receptor targeted inhibitor of the thymidylate synthase, and ONX 0912, an oral proteasome inhibitor, are currently in Phase 1 testing.

    The Earth Times Online Newspaper

  • ONX 0801, an alpha-folate receptor targeted inhibitor of thymidylate synthase, and ONX 0912, an oral proteasome inhibitor, are currently in Phase 1 testing.

    Onyx Pharmaceuticals Announces Data Presentations Highlighting Carfilzomib Development Program at 52nd American Society of Hematology Annual Meeting - Yahoo! Finance

  • Prior to the team's discovery, it was thought that thymidylate synthase, or TS, was the primary enzyme catalyzing a reaction that produced one of the four DNA building blocks called deoxy-thymidine monophosphate.

    EurekAlert! - Breaking News

  • The chemical reaction discovered by the researchers uses an enzyme called flavin-dependent thymidylate synthase, or FDTS.

    EurekAlert! - Breaking News

  • Cartoon diagram of a Thermotoga maritima bacterium flavin-dependent thymidylate synthase, or FDTS, enzyme, which is an example of the class of FDTS enzymes.

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  • Amnon Kohen, associate professor of chemistry in the UI College of Liberal Arts and Sciences, said that the study indicated a new mechanism by which certain organisms manufacture the DNA base thymidylate.

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  • Here we report an example of thymidylate biosynthesis that occurs without an enzymatic nucleophile.

    Naturejobs - All Jobs

  • Biosynthesis of the DNA base thymine depends on activity of the enzyme thymidylate synthase to catalyse the methylation of the uracil moiety of 2′-deoxyuridine-5′-monophosphate.

    Naturejobs - All Jobs

  • These observations indicate a very different chemical cascade than that of classical thymidylate synthases or any other known biological methylation.

    Naturejobs - All Jobs

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