from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun medicine The production of
thymocytes, which later become T cells
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Vascularized thymic lobe allografts support thymopoiesis.
Heinzel K, Bleul CC (2007) The Foxn1-dependent transcripts PCOLCE2 and mPPP1R16B are not required for normal thymopoiesis.
Panoskaltsis-Mortari A, Kuro OM, Hollander GA, Blazar BR, et al. (2007) Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging.
As a growth factor and cytokine physiologically produced by marrow or thymic stromal cells and other epithelia, IL-7 has an important and, at some steps, a non-redundant stimulating effect on T lymphocyte development, notably on thymopoiesis and, down-stream from the thymus, on homeostatic expansion of peripheral T cells.
In addition, we utilized the chimeric severe combined immunodeficient mouse/human (SCID-hu) system in which mice are transplanted with human fetal thymus and liver under the renal capsule, forming a conjoint human organ that phenotypically and functionally recapitulates human thymopoiesis within the mouse
Withers-Ward ES, Amado RG, Koka PS, Jamieson BD, Kaplan AH, et al. (1997) Transient renewal of thymopoiesis in HIV-infected human thymic implants following antiviral therapy.
Kitchen SG, Killian S, Giorgi JV, Zack JA (2000) Functional reconstitution of thymopoiesis following HIV infection.