Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A drug that blocks platelet aggregation, C14H14ClNS, used in its hydrochloride form to prevent stroke and to treat intermittent claudication.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun medicine A particular thienopyridine drug

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[t(h)i(o)– + c(h)lo(ro)– + p(yr)idine.]

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Examples

  • These include two antidepressants: fluoxetine (Prozac, Sarafem, and generic) and fluvoxamine; three anti-fungal drugs: fluconazole, ketoconazole, voriconazole; the blood thinner, ticlopidine; the epilepsy drug, felbamate; and the HIV drug, etravirine.

    Avoid dangerous combination: Blood thinner Plavix with some heartburn drugs 2009

  • These include two antidepressants: fluoxetine Prozac, Sarafem, and generic and fluvoxamine; three anti-fungal drugs: fluconazole, ketoconazole, voriconazole; the blood thinner, ticlopidine; the epilepsy drug, felbamate; and the HIV drug, etravirine.

    Avoid dangerous combination: Blood thinner Plavix with some heartburn drugs 2009

  • Patients with HRPR as assessed by adenosine diphosphate test 70 percent platelet aggregation or greater received an increased dose of clopidogrel or switched to the antiplatelet drug ticlopidine under adenosine diphosphate test guidance.

    unknown title 2011

  • Patients who were found to have high residual platelet reactivity HRPR received a larger dose of clopidogrel or were switched to ticlopidine.

    unknown title 2011

  • Indeed, Berger and colleagues at Geisinger have a paper in press suggesting that more than 20\% of patients allergic to clopidogrel are also allergic to ticlopidine.

    theHeart.org 2009

  • Patients in the study will remain on their usual heart disease medicines, including statins to lower cholesterol, antiplatelet medications such as aspirin, ticlopidine and clopidgrel to reduce clotting and other medications to lower blood pressure or reduce heart rate.

    Baylor College of Medicine News 2009

  • After development, ticlopidine was approved in the US for use as an anti-thrombotic agent.

    Patent Baristas 2009

  • After development, ticlopidine was approved in the US for use as an anti-thrombotic agent.

    Patent Baristas 2009

  • This was approved but had possible adverse effects of rarely occurring but serious blood disorders, neutropenia and thrombotic thrombocytopenic purpura, associated with prolonged usage of ticlopidine.

    Patent Baristas 2009

  • He added that some physicians with a "truly allergic" patient will often switch them to ticlopidine, which has its own host of problems, since it is much more poorly tolerated and chemically similar.

    theHeart.org 2009

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