Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An
oral VEGF receptor tyrosine kinase inhibitor .
Etymologies
Sorry, no etymologies found.
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Examples
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The drug candidate, tivozanib, is being tested in a head-to-head study against an approved drug, Nexavar, marketed by Bayer Healthcare, to treat renal-cell carcinoma.
unknown title 2011
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The company's lead product candidate, tivozanib, is currently being investigated in a global, randomized Phase 3 clinical trial called TIVO-1 comparing tivozanib to sorafenib in patients with advanced renal cell carcinoma, as well as additional clinical studies in other solid tumor types.
unknown title 2011
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The company's lead product candidate, tivozanib, is currently being investigated in a global, randomized Phase 3 clinical trial called TIVO-1 comparing tivozanib to sorafenib in patients with advanced renal cell carcinoma, as well as additional clinical studies in other solid tumor types.
unknown title 2011
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The company's lead product candidate, tivozanib, is currently being investigated in a global, randomized Phase 3 clinical trial called TIVO-1 comparing tivozanib to sorafenib in patients with advanced renal cell carcinoma, as well as additional clinical studies in other solid tumor types.
unknown title 2011
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Investors are excited about its promising kidney cancer drug tivozanib, and the company has other cancer-fighting drugs in earlier-stage trials, as well.
unknown title 2011
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It's not clear yet whether the patients living longer are those on tivozanib or Nexavar.
unknown title 2011
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TIVO-1 is a global, randomized (1: 1), controlled trial evaluating tivozanib compared to sorafenib.
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"We are very pleased to see TIVO-1 reach our enrollment target six months ahead of schedule, and I want to thank our investigators for their enthusiastic support for and tremendous commitment to the development of tivozanib," said Tuan Ha-Ngoc, president and chief executive officer of AVEO.
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The primary endpoint of the trial is to compare the progression-free survival (PFS) of tivozanib vs. sorafenib.
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A Phase 1b trial evaluating tivozanib as monotherapy in patients with non-small cell lung cancer is also being conducted.
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