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torsades de points


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  • A cardiac arrhythmia, usually stemming from prolongation of the QT-interval on an electrocardiogram. In severe instances, it can lead to blackouts, and even death. A common cause is an adverse reaction to certain classes of drugs, particularly those that prolong the QT-interval by blocking potassium channels. Also common in individuals with genetic mutations in genes that control expression of sodium or potassium channels and is a frequent cause of sudden death in these individuals.

    November 12, 2007