toxicogenomics love

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The study of the toxic effects of substances on genetic material, with an attempt to use this information to predict its toxic effect on organisms

Etymologies

Sorry, no etymologies found.

Examples

  • Before Tox21, physiologically based pharmacokinetic (PBPK) models, toxicogenomics, and related approaches were already making risk assessment more mechanistically based.

    Toxicity testing- new dimensions

  • The use of "omic" technology to study toxicological questions is called toxicogenomics.

    Computational toxicology

  • This study sheds new insight into the toxicogenomics of NNK and further supports the hypothesis that genetic components in the metabolism and disposition machines of NNK are modifiers of risk of lung cancer.

    GEN News Highlights

  • "GeneGo's unique approach of generating functional descriptors is a great complement to the classifiers and predictive models in DrugMatrix, and we see great benefit to the scientific community using predictive toxicogenomics."

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  • March 17, 2009 / PRNewswire / -- GeneGo, Inc., the leading provider of pathway data mining & analysis solutions, today announced a license agreement with Entelos of Foster City, CA, a company specializing in predictive technologies, including toxicogenomics and PhysioLab (R) virtual human disease models.

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  • Saito K, Oeda K, Otsuka M, Tsujimura K, et al. (2007) Optimization of an animal test protocol for toxicogenomics studies (ii); a cross-laboratory gene expression analysis.

    PLoS ONE Alerts: New Articles

  • Saito K, Oeda K, Otsuka M, Tsujimura K, et al. (2007) Optimization of an animal test protocol for toxicogenomics studies (I); requirement study of a protocol.

    PLoS ONE Alerts: New Articles

  • Our toxicogenomics approach is different because of its unique economy of scale and use of standardized operating procedures for assay consistency. "

    GEN News Highlights

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