toxicokinetics love

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The application of pharmacokinetics to the study of toxicity

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

toxico- +‎ kinetics

Examples

  • Frequently the terms toxicokinetics, pharmacokinetics, or disposition may be found in the literature to have the same meaning.

    Toxicokinetics

  • 'toxicokinetics', Positive results in one or more mutagenicity has been outlined in an ICH guideline (Federal assays do not necessarily translate into human Register, 1 March 1995).

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  • However, metabolism is sometimes not specific for the transformation process but may include other phases of toxicokinetics.

    Biotransformation

  • Disposition is often used in place of toxicokinetics to describe the time-course of movement of chemicals through the body (that is, how does the body dispose of a xenobiotic?).

    Toxicokinetics

  • Examples of how toxicokinetics of a substance can influence its toxicity:

    Toxicokinetics

  • The toxicokinetics literature is extensive and a listing of all the excellent toxicology and toxicokinetics textbooks is beyond the scope of this tutorial.

    Toxicokinetics

  • The potency of a chemical, or how toxic it is, depends upon its movement through the body to the target site (toxicokinetics); its ability to interact with the body to cause harm (toxicodynamics); and the dose the body receives (exposure level), which is in turn modified by the toxicokinetics and toxicodynamics of the chemical.

    Toxicology

  • Moreover, the species differences in toxicokinetics, whereby BPA as parent compound is less bioavailable in humans than in rodents, raise considerable doubts about the relevance of any low-dose observations in rodents for humans.

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  • This glossary contains definitions of 355 terms frequently used in the multidisciplinary field of toxicokinetics.

    108959041568439494 « ResourceShelf

  • The glossary is compiled primarily for chemists who find themselves currently working in toxicology and requiring a knowledge of the expressions used in toxicokinetics, especially in relation to hazard and risk assessment.

    108959041568439494 « ResourceShelf

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