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from Wiktionary, Creative Commons Attribution/Share-Alike License

  • v. Present participle of transactivate.
  • adj. That stimulates a host cell by transactivation


Sorry, no etymologies found.


  • The objective of this study was to quantify the nuclear localization and DNA binding activity of p65, the major transactivating nuclear factor-kappa B (NF-kappaB) subunit, in full-thickness fetal membranes (FM) and myometrium in the absence or presence of term or preterm labor.

    BioMed Central - Latest articles

  • N-term β-catenin (1-567 aa), and SATB1 or empty vector in indicated combinations. β-catenin proteins encoded by both these constructs can translocate into nucleus and are therefore capable of transactivating Wnt/TCF/β-catenin targets; however, the N-term (1-576) protein does not interact with SATB1.

    PLoS Biology: New Articles

  • The AF2 domain recruits cofactors necessary for NR5A1 transactivating activity.

    New England Journal of Medicine

  • Through this mechanism, PKR can modulate transcription, as revealed by its ability to prevent the capacity of RHA to catalyze transactivating response


  • The transactivating module of NFAT5 switches its function from an stimulus-specific activator of transcription in interphase to an stimulus-independent repressor of binding to DNA in mitosis.

    PLoS ONE Alerts: New Articles

  • Hinchliffe S, Sommer MH, Zerboni L, et al. (2003) Mutational analysis of open reading frames 62 and 71, encoding the varicella-zoster virus immediate-early transactivating protein, IE62, and effects on replication in vitro and in skin xenografts in the SCID-hu mouse in vivo.

    PLoS ONE Alerts: New Articles

  • Because of the presence of two promoters, p63 encodes two major classes of proteins: those containing a transactivating (TA) domain homologous to the one present in p53 (i.e. TAp63), and those that lack the TA domain (i.e. ΔNp63) [1], [2].

    PLoS ONE Alerts: New Articles

  • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, et al. (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.

    PLoS ONE Alerts: New Articles

  • Our present study demonstrates that Foxo3a can regulate cardiomyocyte hypertrophy through transactivating catalase.

    Journal of Biological Chemistry current issue


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