trifluoroacetic love

trifluoroacetic

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The univalent radical derived from acetic be replacing every hydrogen atom with one of flourine

Etymologies

Sorry, no etymologies found.

Examples

  • It appears that one molecule of the anhydride associates with or favors an ionic adduct with one molecule of the lysergic which contains a basic nitrogen atom and that it is the adduct which reacts with a second molecule of trifluoroacetic anhydride to form the mixed anhydride along with one molecule of trifluoroacetic acid.

    L.S.D., R.I.P.

  • A solution of the mixed anhydride of lysergic acid and trifluoroacetic acid in 200 ml. of acetonitrile is obtained by reacting 5.36 g. d-lysergic acid and 8.82 g. trifluoroacetic anhydride in accordance with the procedure of example one.

    L.S.D., R.I.P.

  • The mixture is maintained in a low temperature for about one to three hours to insure the completion of the formation of the mixed anhydride of lysergic and trifluoroacetic acids.

    L.S.D., R.I.P.

  • The mixed anhydride itself, since it contains a lysergic acid group, also can exist in the reaction mixture in large part as an ionic adduct with trifluoroacetic anhydride or trifluoroacetic acid.

    L.S.D., R.I.P.

  • Dispersants suitable for the purpose of this invention are those which are liquids at the low temperatures employed for the reaction and are of such an inert nature that they will not react preferentially to the lysergic acid with trifluoroacetic anhydride.

    L.S.D., R.I.P.

  • Two gallons of trifluoroacetic anhydride are required per mol. of lysergic acid for the rapid and complete conversion of the lysergic acid into the mixed anhydride.

    L.S.D., R.I.P.

  • By my invention I have provided a simple and convenient method of preparing lysergic acid amides, which comprises reacting lysergic acid with trifluoroacetic anhydride to produce a mixed anhydride of lysergic and trifluoroacetic acids, and when reacting the mixed anhydride with a nitrogenous base having at least one hydrogen linked to nitrogen.

    L.S.D., R.I.P.

  • The mixed anhydride of lysergic and trifluoroacetic acids is relatively unstable, especially at room temperature and above, and must be stored at a low temperature.

    L.S.D., R.I.P.

  • A solution of the mixed anhydride of lysergic acid and trifluoroacetic acid is prepared from 2.68 g. of d-lysergic acid and 4.4 g. of trifluoroacetic acid anhydride in 100 ml. of acetonitrile by the method of Example One.

    L.S.D., R.I.P.

  • The reaction of the lysergic and the trifluoroacetic anhydride is a low temperature reaction, that is, it must be carried out at a temperature below about 0 degrees C.

    L.S.D., R.I.P.

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